Recently, Berthold Technologies, a manufacturer of analytical instruments, recently introduced the second-generation multi-label TriStar microplate reader. The TriStar microplate reader has a patent for the ALL-4-ONE optical concept. For the first time, luminescence, fluorescence, and absorbance measurements have been performed. The instrument features a universal detector with extremely low noise in fluorescence emission measurements.

It is reported that the scope of this instrument mainly includes: enzyme activity, phagocytosis, calcium flux, cell viability, apoptosis, immunoassay, protein and DNA concentration and other measurements. The second-generation TriStar microplate reader also has the ability to fluoresce resonance energy transfer (FRET) and bioluminescent resonance energy transfer (BRET). Compared with a generation of products, it has a stronger fluorescence detection limit, specifically less than 6*10^18 moles of adenosine triphosphate (ATP) per strand, and less than 0.3*10^-15 moles of fluorescein per strand .

German Berto is a world-renowned manufacturer of luminescence detection analyzers. The company's products and businesses include: luminometers, microplate luminometers, luminometers, fluorescence detectors, photometers, luminescence imaging systems, and high-pressure liquid chromatography. Radioisotope detector, gamma gamma counter, mechanical arm, radiation protection monitor, etc.